Scientists Identify Sub-Type Of Lethal Prostate Cancer

Scientists Identify Sub-Type Of Lethal Prostate Cancer
shutterstock_153496376Researchers at Upstate Medical University and Harvard University recently revealed that the loss of the WAVE1 gene is related to a lethal form of prostate cancer. The study was funded by the National Institutes of Health and the Department of Defense and published in the Oncotarget journal. Prostate cancer is the most frequent type of cancer affecting men and is responsible for 27,000 deaths each year and a total of 220,000 new cases diagnosed annually. Several databases available to the public were compared using bioinformatic meta-analysis tools. Scientists found that modifications in the WAVE1 gene were related to smaller periods of remission in patients treated for prostate cancer. Importantly, the assessment revealed that 22.9 percent of prostate cancer cases analyzed had the WAVE1 gene deletion. Leszek Kotula, the study's co-author and professor at Upstate Medical University in Syracuse, N.Y., said in a press release: “We observed that prostate cancer tumors contain a frequent deletion of the WAVE 1 gene. What's important, though, is that this WAVE1 gene deletion occurs in metastatic and lethal cancer, thus suggesting that, the WAVE1 gene loss may represent an aggressive sub
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Isaura Santos graduated with a BS in Cell and Molecular Biology from Universidade Nova de Lisboa and a MA in Communication, Culture and Information Technologies from University Institute of Lisbon (ISCTE-IUL). Her professional interests include science communication, public awareness of science and communication of science through entertainment.

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