Deadly Prostate Cancer May Best Be Avoided with Exercise, Healthy Diet

Deadly Prostate Cancer May Best Be Avoided with Exercise, Healthy Diet
Specific lifestyle factors, like engaging in vigorous physical activity, maintaining a healthy body weight, not smoking, and eating plenty of fatty fish, may reduce the risk of developing prostate cancer, researchers reported. The study, published in the Journal of the National Cancer Institute, is titled “Development and Application of a Lifestyle Score for Prevention of Lethal Prostate Cancer.” Prostate cancer is the most frequently diagnosed cancer and the second leading cause of cancer deaths among men in the United States. Most prostate cancer patients are diagnosed with clinically indolent tumors without lethal potential, but several lifestyle factors have been associated with more deadly forms of the disease. To develop and apply a lifestyle score of activities that lower such a risk, Stacey A. Kenfield, from the University of California San Francisco, and colleagues analyzed data from the Health Professionals Follow-up Study (HPFS) and the Physicians’ Health Study (PHS). The team developed its score among 42,701 men in the HPFS group and applied it among 20,324 men in the PHS group. One point was given for each key activity: currently not smoking or having quit 10 or more years ago, body mass index under 30kg/m2, high vigorous physical activity, high intake of tomatoes and fatty fish, and low intake of processed meat. The analysis included a calculation of diet-only scores (range = 0–3) and total scores (range = 0–6). A multivariable Cox proportional hazards regression was used to estimate the risk of lethal prostate cancer, adjusting for potential risk factors of such cancer. Among men in both groups, 913 lethal prostate cancer events (576 from HPFS and 337 from PHS) were identified. In the HPFS group, results showed that men w
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