Improved Prostate Cancer Detection, Surgeries Possible With Novel Light Reflectance Technique

Improved Prostate Cancer Detection, Surgeries Possible With Novel Light Reflectance Technique
Researchers at the University of Texas Southwestern Harold C. Simmons Comprehensive Cancer Center in Dallas have determined that an emerging optical-based endoscopic technique called light reflectance spectroscopy can enable surgeons to rapidly and safely evaluate prostate tissue with 85 percent accuracy without excision to distinguish whether it is malignant or benign. The scientists' discovery, which measures light intensity reflected or back-scattered from tissues, could potentially lead to real-time tissue analysis as a standard part of prostate cancer surgery. Benefits of using the light reflectance spectroscopy procedure include its facilitation of highly accurate surgical removal of cancerous tissue while sparing more healthy tissue, thereby minimizing likelihood of the cancer recurring and reducing necessity for additional treatment. However, researchers caution that more follow-up study is needed before this procedure can become a routine element of prostate cancer surgery. "We used a novel light reflectance spectroscopy probe to evaluate surgical margins on radical prostatectomy tissue specimens and correlated the findings with pathological examination," said UT Southwestern Professor of Urology and Radiology Dr. Jeffrey Cadeddu, lead author of a paper describing the study recently published in the Journal of Urology. Titled "Light Reflectance Spectroscopy to Detect Positive Surgical Margins on Prostate Cancer Specimens," the paper is co-authored by Cadeddu with UTSW assistant instructor of urology Dr. Aaron Lay; associate professor of pathology and urology Dr. Payal Kapur; Dr. Claus Roehrborn, chairman of urology and holder of the E.E. Fogelson and Greer Garson Fogelson Distinguished Chair in Urology and the S.T. Harris Family Chair in Medic
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