Prostate Cancer Study Finds Little Difference Between Active Monitoring and Agressive Treatment Over 10 Years

Prostate Cancer Study Finds Little Difference Between Active Monitoring and Agressive Treatment Over 10 Years
Active monitoring of patients with localized prostate cancer is as effective as surgery and radiotherapy in terms of 10-year survival after diagnosis, according to findings from the largest prostate cancer study in the U.K.  But treatment, in the form of surgery or radiotherapy, was also seen to reduce the risk of cancer progression and spread. The findings may affect future policy decisions on screenings for prostate cancer, and offer men with the prostate cancer and their doctors better guidelines for managing the disease. The study gave rise to two publications: “10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer, and “Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer,” both published in the New England Journal of Medicine. “What we have learnt from this study so far is that prostate cancer detected by prostate specific antigen blood test grows very slowly, and very few men die of it when followed up over a period of 10 years — around 1% — irrespective of the treatment assigned,” Freddie Hamdy, a professor at the University of Oxford and chief investigator of the study, said in a news release. “This is considerably lower than anticipated when we started the study.” The ProtecT trial (NCT02044172), running for 10 years
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One comment

  1. Robert Hess says:

    I’m not sure what conclusion to take from this report. Men without treatment experienced twice the rate of spread of the disease but they died at the same rate and timeline?

    Is the correct conclusion that for life expectancy treatment does not matter but can help with quality of life toward the end when the cancer has spread?

    I thought to kill you the cancer needed to grow and spread? Or perhaps the cancer that is treated only becomes aggressive and spreads towards the end?

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