Researchers Indentify 3 Prostate Cancer Molecular Subtypes Paving Way to Individualized Care

Researchers Indentify 3 Prostate Cancer Molecular Subtypes Paving Way to Individualized Care
Researchers have identified and confirmed three separate molecular subtypes of prostate cancer that associate with metastasis-free survival and can predict how patients respond to treatments. The results of the study, the largest of its kind to date, were presented at the American Society for Radiation Oncology 2016 Annual Meeting, held Sept. 25-28, in Boston. Titled "Identification and Validation of Intrinsic Subtypes of Prostate Cancer," the study may help bridge the gap between today's therapeutic options and future individualized approaches in prostate cancer care. Even though there are several ways to diagnose and treat  (rectal exam, the prostate specific antigen (PSA) levels in a man's blood, and a prostate tumor biopsy) the molecular classification of tumor cells is what truly helps oncologists come up with a personalized treatment plan for each cancer patient. "Tumors that appear similar under a microscope can behave very differently, from a clinical standpoint," Dr. Daniel E. Spratt, lead author of the study and chief of the Genitourinary Radiotherapy Program at the University of Michigan in Ann Arbor, Michigan, said in a press release. "One promise of genomic analyses is to elucidate subtypes of cancer based on the genetics of the tumor rather than merely how they look or what size they are." The investigators gathered 4,236 samples from
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