MNX1 Gene May Account for Higher Prostate Cancer Occurence Among African-Americans

MNX1 Gene May Account for Higher Prostate Cancer Occurence Among African-Americans
Scientists have identified a gene, called MNX1, that may account for the increased incidence of prostate cancer among African-American patients, according to a new study published in the journal Cancer Research. The study, “MNX1 Is Oncogenically Upregulated in African-American Prostate Cancer,” supports the idea that certain genetic factors are responsible for differences in prostate cancer incidence among men from distinct ethnic groups. The findings suggest MNX1 could become a valuable biomarker for diagnosis. "African-Americans have about one-and-a-half times the incidence and twice the mortality associated with prostate cancer of European Americans, and the reasons for this are not clear," Michael Ittmann, MD, PhD, senior author of the study, said in a news release. Ittmann is a professor of pathology and immunology at Baylor University College of Medicine and the Michael E. DeBakey Department of Veterans Affairs Medical Center. Together with genetics, socio-economic factors also account for the differences in disease occurrence. For instance, less access to healthcare services may mean less regular examinations and screenings for prostate cancer among African-American men. To investigate genetic differences causing prostate cancer between African-American and European-American men, researchers analyzed the genetic profile of tissue samples from patients of those ethnic groups. "We found 24 genes that were different between the African-American and the
Subscribe or to access all post and page content.

Tagged , , , , .

Joana brings more than 8 years of academic research and experience as well as Scientific writing and editing to her role as a Science and Research writer. She also served as a Postdoctoral Researcher at the Center for Neuroscience and Cell Biology in Coimbra, Portugal, where she also received her PhD in Health Science and Technologies, with a specialty in Molecular and Cellular Biology.

Leave a Comment

Your email address will not be published. Required fields are marked *