Risk Factors for Prostate Cancer May Be Influenced by Biopsy Bias, Researchers Say

Risk Factors for Prostate Cancer May Be Influenced by Biopsy Bias, Researchers Say
Risk factors for prostate cancer may not be what researchers believed. According to a study published recently in the Journal of Clinical Oncology, biases exist in screening and biopsy patterns, and those biases strongly influence the assessment of prostate cancer risk factors. The study, "Biases in Recommendations for and Acceptance of Prostate Biopsy Significantly Affect Assessment of Prostate Cancer Risk Factors: Results From Two Large Randomized Clinical Trials," suggests that risk factors derived from epidemiologic studies, where not all participants are equally likely to undergo screening, may be erroneous and lead to misdirected research efforts. Prostate cancer is the second most common cause of cancer death in men, and efforts that aim to control it include prevention, screening and improved treatment. Usually, prostate cancer prevention and early detection rely on the assessment of a patient's risk to determine how often he should undergo PSA screening or a prostate biopsy. But such risk factors are identified in epidemiologic studies and implemented in the clinic without confirmatory clinical trials. As a result, researchers in this study learned that even risk factors that are not associated with prostate cancer will be found to increase cancer risk. That is because men with the risk factor are more likely to undergo screening and be diagnosed with prostate cancer. "We assumed that prostate cancers are diagnosed uniformly, but that's not true," Catherine Tangen, DrPH, of the Fred Hutchinson Cancer Research Center, and the lead
Subscribe or to access all post and page content.

3 comments

  1. This was a confusing and poorly written article. Exactly what were you trying to say? If you were talking about screening using only PSA and biopsies you are behind the times severely. If you are saying that the current state of screening in the medical community is a mess you are correct. How many Doctors utilize PCA3, free testosterone, and the new 3T MRI or even color doppler ultrasound guided biopsies? Then there is the scandal of related age to PSA which insults older men with the implication that their lives are less valuable than a younger man. Finally how many Doctors require of their patients a who have an first PSA that they return in 6 months to have another one to establish a “baseline” for accurate doubling time analyis? I have been researching in this field for 15 years and the best book on the entire subject is by a recent patient “An ABC of Prostate Cancer” by Alan G. Lawrenson, read it.

  2. Lukas Barbaglia says:

    I really dont know that much about this topic and I know very little about the risks and complications from BPH treatments, thats why when my doctor told me about surgery I just did avoit it and told him i didnt wan to go through it so He gave another option, a natural treatment based on a better alimentation and a natural supplement named alpha rise, i think natural remedies are better and have less side effects, it helped me a lot.

    • Tim Bossie says:

      Absolutely Lukas. Natural remedies have their place in the treatment of diseases like cancer. However, there are people, and situations, when pharmaceutical treatments and surgeries can not be avoided. Glad to hear you are doing well!

Leave a Comment

Your email address will not be published. Required fields are marked *