Rare Childhood Disease Helping to Unravel How PTEN Mutations Affect Prostate and Other Cancers

Rare Childhood Disease Helping to Unravel How PTEN Mutations Affect Prostate and Other Cancers
Researchers have found a link between the rare childhood disease, called Fanconi anemia, and a major cancer gene, known as PTEN, that is often mutated in brain, uterine, and prostate cancers. In the study, “The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair,” they show that Fanconi anemia proteins and PTEN

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