Mutations in SPOP Protein Trigger Onset of Prostate Cancer Subtype, Study Finds

Mutations in SPOP Protein Trigger Onset of Prostate Cancer Subtype, Study Finds
Mutations in a protein called SPOP trigger the development and growth of a subtype of prostate cancer, according to a study. The findings may lead to treatments targeting the subtype, researchers said. The study, “SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling,” was published in the journal Cancer

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