Scientists Find Genes That Could Work Together to Suppress Prostate Cancer

Scientists Find Genes That Could Work Together to Suppress Prostate Cancer
Scientists at the Wellcome Trust Sanger Institute in the United Kingdom and collaborators have identified genes that could help prevent prostate, skin, and breast cancer. Their goal was to find genes that cooperate with the well-known tumor suppressor gene PTEN to  create a tumor suppressor network. The study, “A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes,” was published in the journal Nature Genetics. PTEN is an established tumor suppressor. It regulates pathways involved in cells’ grow and division that spin out of
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