Modified Citrus Pectin Shows Potential in Relapsed Prostate Cancer Patients, Study Suggests

Modified Citrus Pectin Shows Potential in Relapsed Prostate Cancer Patients, Study Suggests
Treament with modified citrus pectin (MCP), a nutritional supplement, led to promising results in men with recurrent prostate cancer, according to preliminary results from a Phase 2b trial. The study with the results, "Effect of PectaSol-C modified citrus pectin (P-MCP) treatment (tx) on PSA dynamics in patients (pts) with nonmetastatic, biochemically relapsed prostate cancer (BRPC): Results of the interim analysis of a prospective phase II study," was published in the Journal of Clinical Oncology in conjunction with the 2017 ASCO (American Society of Clinical Oncology) Annual Meeting in Chicago. The protein PSA (prostate specific antigen) is made only by the prostate gland. Although the increase in PSA production is not exclusive to prostate cancer, its measurement is a valuable tool in cancer screening. Therefore, assessing the PSA doubling time (PSADT) is a viable measure of tumor growth in patients whose prostate has been targeted with surgery and/or radiation. The PSADT reflects the time taken by the number of tumor cells to duplicate. Current treatment options for patients with biochemically relapsed prostate cancer (BRPC; rising PSA levels), such as androgen deprivation therapy, have significant toxicity concerns. That's why new non-toxic therapies are being investigated. Pectin is extracted from the pith of citrus fruit peels and is subjected to a modification process to ease its entrance in the bloodstream. PectaSol-C MCP (or P-MCP) inhibits galectin-3, a carbohydrate-binding protein, w
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