Aptevo Regains Rights to Prostate Cancer Therapy APVO414, Whose Results Improve After Delivery Method Tweaked

Aptevo Regains Rights to Prostate Cancer Therapy APVO414, Whose Results Improve After Delivery Method Tweaked
Aptevo Therapeutics has ended its partnership with MorphoSys AG for the development and commercialization of APVO414 as a treatment for metastatic castration resistant prostate cancer, or  mCRPC. The termination means the company has regained the worldwide rights to APVO414, which it will continue evaluating in an ongoing Phase 1 clinical trial of the therapy's safety and effectiveness, and patients' ability to tolerate it. Aptevo said switching participants' treatment regimen in the ongoing trial has led to better results than in the initial Phase 1 trial. Participants are producing fewer anti-drug antibodies -- which neutralize the therapy's effectiveness -- under the new regimen than the old on
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