- Clinicopathological Correlation and Molecular Signature Identification and Risk Stratification of Prostate Cancer in African American U.S. Veterans, With and Without Exposure to Battlefield Chemicals” — $1 million. A team will study prostate cancer samples from veterans to better understand the biology of the disease in African-American men. It will also look at whether exposure to battlefield chemicals such as Agent Orange play a role in the development and progression of the cancer.
- “Curing Lethal Non-Castrate Prostate Cancer: Integrative Molecular Analysis for Mechanisms of Exceptional Response, Resistance and Recurrence” — $1 million. A team will develop a precision medicine approach to treating prostate cancer patients who have a high-risk localized disease or low-volume metastatic tumors. The treatment they will study will be a regimen of androgen-targeted therapies, followed by maximum treatment
Eight teams of researchers will be sharing $7.5 million in research grants from the Prostate Cancer Foundation (PCF). The 2017 PCF Challenge Awards will go to international, cross-disciplinary teams who will conduct innovative studies on critical, unmet medical needs of men with prostate cancer. The winning projects, announced at the 24th Annual PCF Scientific Retreat in Washington Sept.5-7, were: