Comorbidities Increase Mortality from Causes Other than Prostate Cancer, Study Reports

Comorbidities Increase Mortality from Causes Other than Prostate Cancer, Study Reports
The presence of one or more additional diseases (comorbidity) does not affect the risk of dying from prostate cancer, regardless of treatment type, a Swedish observational study reports. However, high comorbidity in prostate cancer patients is linked with increased mortality from other causes. The study, “Effect of Comorbidity on Prostate Cancer–Specific Mortality: A Prospective Observational Study,” was published in The Journal of Clinical Oncology. “Comorbidities are medical disorders that coexist with, but are distinct from, the primary diagnosis,” authors explained. They are usually associated with worsening health outcomes. While researchers have addressed comorbidity in prostate cancer patients, studies have reported conflicting results on its association with prostate cancer mortality. Researchers at the Queen Mary University of London, England, and the Karolinska Institute in Stockholm, Sweden, and colleagues investigated the effect of comorbidities on prostate cancer-specific mortality after accounting for patient and tumor characteristics. Treatment type was also taken into account in their analysis. These included radical prostatectomy (a surgical procedure for removing the prostate gland); radical radiotherapy (a non-surgical treatment using radiation); androgen deprivation therapy, and watchful waiting (a strategy that monitors prostate cancer that isn't causing any symptoms and avoids treatment unless it becomes symptomatic). The study included 118,543 prostate cancer patients
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One comment

  1. Stephen B. Strum, MD, FACP says:

    Here’s the problem with ALL of our health issues. We have specialists who either do not wish to see an illness as a manifestation of both genetic + epigenetic causes or who do not wish to “infringe” on the specialties of other specialists. What we have is a myopic view of the patient’s health that misses the interactions aka systems biology, that is inherent in all of life. Everything is interactive; that’s why whoever coined the term uni-verse (one story) was a person of vision or prescience. What is being called wholistic medicine or integrative medicine (see ) is really missing the mark.

    Interactive medicine looks intensely into the systems that interact with the disease that is currently most threatening to the patient. What circumstances on a biological level has created this disease scenario? When physicians look at prostate cancer & see the interaction of prolonged glycation, abnormal fatty acids, high oxidized LDL, suboptimal Vit D, bone-derived growth factors that stimulate cancer growth in a vicious cycle of bone loss and cancer growth stimulation, and all the interplay with the above & cardiovascular disease, renal, neurological, musculoskeletal health etc, then publications such as the one by Rajan et al on:
    Effect of Comorbidity on Prostate Cancer–Specific Mortality: A Prospective Observational Study can focus on what matters most: the quality & quantity of the patient’s life, no matter what the presenting disease.

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