Baseline PSA Screening During Midlife Predicts Prostate Cancer in Black Men, Study Finds

Baseline PSA Screening During Midlife Predicts Prostate Cancer in Black Men, Study Finds
Measuring PSA levels during midlife — between 40 and 64 years — could help predict the likelihood an African-American man has of developing prostate cancer up to 12 years after the analysis, a study shows. The study, "Baseline Prostate-specific Antigen Level in Midlife and Aggressive Prostate Cancer in Black Men," was published in the journal European Urology. The prostate-specific antigen (PSA) is an enzyme produced by the prostate gland that has long been used to diagnose prostate cancer. The test originally was approved in 1986, but studies since suggest it also could lead to the diagnosis and treatment of cancers that may present no harm to patients; that is called over-diagnosis. So, researchers have proposed that men undergo PSA testing during midlife to determine their risk of prostate cancer and the frequency of additional screening. If men have elevated PSA levels — higher than average, but still under normal values — they should receive more frequent screening, whereas those with lower PSA levels could receive minimal or no screening going forward. Indeed, multiple studies have shown that measuring PSA levels from 40 to 60 years strongly predicts prostate cancer incidence and risk of death several decades after testing. However, most of the data come from studies involving white men, with only two studies examining this approach in black men. Now, researchers aimed to determine if measuring PSA levels during midlife could predict prostate cancer risk in black men, focusing particularly on aggressive cancers. "Black men in the U.S. are 2.5 times more likely to die of prostate cancer com
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2 comments

  1. Christopher O'Neill says:

    Detecting any type of Prostate Cancer is quite easy. Actually saving lives from Prostate Cancer is entirely far more difficult and uncertain.

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