Radiation Treatments Delay Metastasis, Recurrence in Aggressive Prostate Cancers

Radiation Treatments Delay Metastasis, Recurrence in Aggressive Prostate Cancers
Radiation therapy approaches — including external beam radiation therapy (EBRT) and brachytherapy — for prostate cancer patients with aggressive disease are better at extending the time to metastasis or cancer recurrence than prostate surgery, a study shows. The findings were presented at the American Society for Radiation Oncology (ASTRO) 2018 Annual Meeting, held Oct. 21-24 in San Antonio, Texas. The study was titled "Comparative Effectiveness of Prostatectomy and Radiation Therapy (RT) in Gleason 9-10 Prostate Cancer." Prostate cancer with a Gleason score — a measure of how aggressive a cancer is — of 9 or 10 is an aggressive cancer with a high likelihood of spreading. Patients usually have a radical prostatectomy — where the prostate and surrounding tissues are surgically removed — but recent studies suggest that EBRT with a brachytherapy boost is better at delaying biochemical relapse, deemed as rising PSA levels. EBRT is a type of radiation therapy where high-energy radiation beams are delivered into tumors, accounting for their contours. This is better than traditional radiation treatments, as it helps reduce damage to healthy tissue and nearby organs. Brachytherapy consists of small radiation "seeds" that are implanted directly into tumors. This kind of internal radiation therapy — which can be implanted temporarily or permanently — allows the use of higher total radiation doses delivered in shorter periods than EBRT. To see whether these kinds of radiation therapy outperformed radical prostatectomy, researc
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