Finasteride Use Before Prostate Cancer Diagnosis Linked to More Advanced Disease, Lower Survival, Study Finds

Finasteride Use Before Prostate Cancer Diagnosis Linked to More Advanced Disease, Lower Survival, Study Finds
Patients who take finasteride before being diagnosed with prostate cancer tend to have more advanced and aggressive disease, as well as lower overall survival, according to a large, national study. The study, “Association Between Finasteride use Prior to Prostate Cancer Diagnosis and Prostate Cancer-Specific Survival,” was presented at the recent American Society for Radiation Oncology 2018 Annual Meeting. Finasteride, marketed under the brand names Propecia and Proscar, is frequently used to treat hair loss and prostate gland enlargement. Although prior research indicated it may also reduce the risk of low-grade prostate cancer, patients taking finasteride who develop prostate cancer seem to have more aggressive disease. Aiming to determine if finasteride is associated with increased prostate cancer-specific mortality (PCSM), a team from the University of California San Diego examined data from 111,933 prostate cancer patients included in the national Veterans Affairs database. Participants had been diagnosed between 2000 and 2015, and 11,085 of them had taken finasteride before diagnosis. The investigators conducted a thorough evaluation of patients’ sociodemographic data, including their marital status, employment status, age, race, ZIP code, income, education, and body mass index, as well as alcohol and
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José is a science news writer with a PhD in Neuroscience from Universidade of Porto, in Portugal. He has also studied Biochemistry at Universidade do Porto and was a postdoctoral associate at Weill Cornell Medicine, in New York, and at The University of Western Ontario in London, Ontario, Canada. His work has ranged from the association of central cardiovascular and pain control to the neurobiological basis of hypertension, and the molecular pathways driving Alzheimer’s disease.

3 comments

    • Peter Cooperrider says:

      Yes, I believe so, and on the basis of that study, I got my Urologist to prescribe finasteride for me. So what now? 🙁

  1. Jordan says:

    The previous study that was released this year invalidates this one. This follow up is much shorter and about three times as small. It’s sort of irresponsible to publish this info in my opinion. Probably clickbait driven.

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