High Vegetable Diet Does Not Halt Prostate Cancer, Study Finds

High Vegetable Diet Does Not Halt Prostate Cancer, Study Finds
Contrary to popular opinion, eating a diet high in vegetables does not reduce the risk of prostate cancer progression in men with early-stage disease, findings from a Phase 3 trial show. The trial included men managed with active surveillance, in which patients are monitored carefully over time for signs of disease progression, allowing them to forgo immediate radical treatment such as surgery or radiation therapy. While the trial failed to meet its primary goal, it showed that active dietary counseling can help patients make better food choices, keeping them healthier for when they undergo cancer treatments.  The study, “Effect of a Behavioral Intervention to Increase Vegetable Consumption on Cancer Progression Among Men With Early-Stage Prostate Cancer,” was published in the Journal of the American Medical Association. Clinical guidelines for men with prostate cancer recommend eating a diet rich in vegetables, as this approach may decrease cancer progression and improve survival, according to some studies, preclinical experiments, and expert opinions. However, data are lacking from randomized clinical trials demonstrating the efficacy of high vegetable diets for prostate cancer patients. To find out if the diet affects cancer progression, a team led by investigators at the University of California San Diego (UCSD) School of Medicine and Roswell Park Comprehensive Cancer Center in Buffalo, designed the Men's Eating and Living (MEAL) Phase 3 study (NCT01238172) to follow men with early-stage prostate adenocarcinoma and determine if increased micronutrient-enriched vegetable consumption affected cancer progression.  The primary analysis included 443 men, between the ages of 50 and 80, diagnosed with early-stage prostate cancer who were split in
Subscribe or to access all post and page content.