New AI Algorithm Can Accurately Identify, Grade Prostate Cancer

New AI Algorithm Can Accurately Identify, Grade Prostate Cancer
A new artificial intelligence (AI) algorithm has been developed that can accurately detect and grade prostate cancer, using slide images from patient core needle prostate biopsies, a study reports. The study, “An artificial intelligence algorithm for prostate cancer diagnosis in whole slide images of core needle biopsies: a blinded clinical validation and deployment study,” was published in The Lancet Digital Health. Analysis of tissue collected during a prostate biopsy is currently the mainstay diagnostic test for prostate cancer. However, an increase in prostate cancer incidence and demand for these diagnostic tests, coupled with a shortage of expert pathologists, has led to the need for an AI-based system that could accurately detect prostate cancer. Researchers from the University of Pittsburgh Medical Center (UPMC), in collaboration with colleagues, have now developed and validated a new AI-based algorithm designed to recognize prostate cancer using tissue slides with patient core needle biopsies (CNBs). They started by “training” the AI algorithm to recognize signs of prostate cancer, using a total of 1,357,480 images, taken from 549 tissue slides. Each slide had been stained with a combination of hematoxylin, which labels cells’ nuclei in blue, and eosin, which labels the cells’ cytoplasm and extracellular matrix in pink. Nuclei are the s
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