5. Aggressive Prostate Cancers Appear to Be Linked to Self-Renewing Stem Cells Within the Prostate
University of Texas MD Anderson Cancer Center researchers have demonstrated that the prostate basal cell layer contains self-renewing adult stem cells, with a gene expression profile which overlaps that of aggressive and endocrine therapy-resistant prostate cancers. These results indicate that such cells might be the cells-of-origin in aggressive prostate cancers, and offer a new option for anticancer therapies.