Lipid Levels Are Associated With Prostate Cancer Risk, According To Study

Lipid Levels Are Associated With Prostate Cancer Risk, According To Study
In a recent study titled “Serum Lipid Profile and Risk of Prostate Cancer Recurrence: Results from the SEARCH Database”, published in the Cancer Epidemiology, Biomarkers & Prevention journal, a group of researchers from Duke University School of Medicine have found that elevated levels of cholesterol and triglycerides after prostate cancer surgery, could be linked with an increased risk of cancer recurrence. The team used the Shared Equal Access Regional Cancer Hospital (SEARCH) database to design a retrospective cohort analysis of 843 radical prostatectomy (RP) patients who had never used statins before surgery. The link between cholesterol, LDL (good cholesterol), HDL (bad cholesterol), triglycerides and biochemical recurrence risk were then assessed. Furthermore, the researchers also analyzed these links in patients who suffered from dyslipidemia, an abnormal amount of lipids in the blood (either in high proportions or low). The results showed that elevated serum triglycerides of 150 mg/dL or higher were associated with a 35% increased risk of prostate cancer recurrence. This risk was not associated with total cholesterol, LDL and HDL levels. Nonetheless, if patients suffered from dyslipidemia, for each 10 mg/dl increase in cholesterol and HDL, there was a 9% increase in recurrence risk and a 39% reduced recurrence risk, respectively. "These findings suggest that normalization, or even partial normalization, of blood fats among men with high cholesterol and triglycerides may reduce the risk of prostate cancer recurrence," lead researcher Emma Allott, a postdoctoral associate at Duke University School of Medicine said in a HealthDay news report. Dr. Anthony D'Amico, chief of radiation oncology at Brigham and Women's Hospital in Boston, wh
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