Obesity May Increase Risk of Progression For patients With Low-Risk Prostate Cancer

Obesity May Increase Risk of Progression For patients With Low-Risk Prostate Cancer
shutterstock_150704639A new study on the association between obesity and prostate cancer entitled “Obesity Is Associated with Risk of Progression for Low-risk Prostate Cancers Managed Expectantly” was published in the European Urology Journal by Dr. Neil E. Fleshner’group from Division of Urology, Department of Surgery, Princess Margaret Hospital, University Health Network, Ontario, Canada. The correlation between obesity and prostate cancer (PCa) occurrence has been a controversial issue, however, several epidemiological studies have shown the existence of multiple associations between obesity and advanced Pca, biochemical recurrence and mortality associated this malignancy. Obesity has been linked to a series of biological alterations, such as hyperinsulinemia, changes in the levels of adipokine, vascular endothelial growth factor and sex hormones, that have a negative impact in cancer risk and progression. In addition, obesity can have del
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