Study Finds Connection Between Prostate Cancer Therapy And Increase In Heart-Related Deaths

Study Finds Connection Between Prostate Cancer Therapy And Increase In Heart-Related Deaths
shutterstock_186087665A new study titled Association of androgen deprivation therapy with excess cardiac-specific mortality in men with prostate cancer, published in the BJU International journal, has showed that some drugs used to treat prostate cancer can increase the risk of dying from heart-related causes in men who have congestive heart failure or have had prior heart attacks. Androgen deprivation therapy (ADT) is commonly used to treat prostate cancer, and its mechanisms of action consist on reducing the levels of male hormones in the patient’s organism to prevent them from stimulating cancer cell’s growth and development. However, despite its success in treating some forms of prostate cancer, ADT has been linked to cardiovascular problems, such as coronary heart disease, heart attacks, and sudden cardiac death. To understand if cardiac-specific mortality  (CSM) was actually connected to ADT treatment, the team of researchers, led by Paul Nguyen, MD, of the Dana-Farber/Brigham and Women's Cancer Center in Boston, along with David Ziehr of Harvard Medical School, analyzed 5,077 men with a median age 69.5 years, th
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