Aggressive Prostate Cancer Treatment Despite Guidelines

Aggressive Prostate Cancer Treatment Despite Guidelines
shutterstock_162942518When men are diagnosed with prostate cancer and have a life expectancy of less than 10 years, national guidelines recommend "watchful waiting" instead of treatment, as patients are unlikely to see added benefits from aggressive treatment, such as radiation or surgery, within 10 years. Regardless of these guidelines, a study from the University of California, Los Angeles, shows that more than half of men with a low life expectancy are treated with radiation therapy. Dr. Timothy Daskivich led the research effort, which involved analyzing health histories of over 96,000 men diagnosed with early-stage prostate cancer and listed in the Surveillance, Epidemiology, and End Results-Medicare database. Approximately half of the men had life expectancies less than 10 years, and the majority were treated with surgery, radiation, or brachytherapy. This may be problematic, as aggressive treatments can lead to poorer quality of life. "Life expectancy is poorly integrated into treatment decision-making for prostate cancer, yet it is one of the primary determinants of whether a patient will benefit from treatment with surgery or radiation," said Dr. Daskivich in a news
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Maureen Newman is a science columnist for Pulmonary Hypertension News. She is currently a PhD student studying biomedical engineering at University of Rochester, working towards a career of research in biomaterials for drug delivery and regenerative medicine. She is an integral part of Dr. Danielle Benoit's laboratory, where she is investigating bone-homing therapeutics for osteoporosis treatment.

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