New MRI Technique Could Help Early Prostate Cancer Detection

New MRI Technique Could Help Early Prostate Cancer Detection
University of Texas Southwestern Medical Center researchers have developed a new MRI technique that is able to detect prostate cancer in its early stages. Prostate cancer tissue releases lower levels of zinc when compared to healthy prostatic tissue, allowing clinicians to differentiate between the two types of tissues. MRI is a non-invasive medical imaging technique that uses harmless magnetic fields and radio waves. It is widely used in hospitals and in clinics for medical diagnosis and to monitor the progression of disease without exposing the body to ionizing radiation. Normal MRI's, however, cannot reliably distinguish between zinc levels in healthy versus cancerous prostate tissue. This new approach uses a novel zinc ion-sensing molecule in conjunction with MRI to detect very low levels of zinc ions released from inside epithelial cells when stimulated with glucose, therefore accurately identifying prostatic tumors. "Prostate cancer often has no early symptoms, so identifying potential new diagnostic methods that might catch the cancer at an earlier stage or allow us to track how it is progressing is an important opportunity," Dr. Neil Rofsky, chairman of radiology, director of translational research for the Advanced Imaging Research Center, and co-author of the study, said in a news release. In their study, “Zinc-sensitive MRI contrast agent detects differential release of Zn(II) ions from the healthy vs. malignant mouse prostate,” published
Subscribe or to access all post and page content.

One comment

  1. Lloyd L Crabtree says:

    In October 2000, I was a patient in the MRI study through the Swedish Urology Group in Seattle, WA. In comparing the MRI results with the post-surgery pathology of my prostate, it was almost 100% accurate. The MRI didn’t identify that the cancer had come through the prostate wall. The ultrasound for the biopsy had only showed a pea size tumor in the right side whereas the tumor was in both sides and on the right, about 2/3 full. My PSA at the time was 4.9

Leave a Comment

Your email address will not be published. Required fields are marked *