Urine Samples Could Help Predict Heart Attacks, Breast and Prostate Cancer, Study Claims

Urine Samples Could Help Predict Heart Attacks, Breast and Prostate Cancer, Study Claims
A new study shows that about 90% of volunteers who donated a urine sample to the Oregon Institute of Science and Medicine had specific metabolic profiles for three distinct conditions: cardiac events, and breast and prostate cancer. All of these urinary patterns appeared before the diseases' subsequent symptoms and medical diagnoses. The study titled, "Metabolic Profiling with Magnetic Resonance Mass Spectrometry and a Human Urine Bank: Profiles for Aging, Sex, Heart Disease, Breast Cancer and Prostate Cancer," was published in the Journal of American Physicians and Surgeons. Metabolic profiling is the measurement of low molecular weight metabolites and their intermediates, which shows dynamic responses to certain stimuli, both in normal and diseased conditions. The concept appeared in the late 1960s and continued throughout the '70s, based largely on the work of Arthur Robinson. Robinson discovered the existence of metabolic profiles for many conditions, including multiple sclerosis and Huntington's disease. Unfortunately, due to limited resources at the time, progress on the research stalled. Nowadays, the Oregon Institute of Science and Medicine has a urine sample bank to which 5,000 volunteers periodically contribute urine specimens and medical histories. As time goes by, samples from patients who develop a medical event of interest accumulate. These are then quantitatively analyzed by magnetic resonance mass spectrometry (MRMS). MRMS simultaneously quantifies over 800 molecular urinary components of human metabolic o
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