Canadians Find Better Way to Screen for Drug-resistant Prostate Cancer

Canadians Find Better Way to Screen for Drug-resistant Prostate Cancer
A new approach to detecting tumor cells in the blood offers a minimally invasive alternative to identifying prostate cancer patients who may not respond to first-line treatments, Canadian researchers report. They said the technology could be used to screen for drug-resistant tumor cells. The study describing their approach, “Single-cell mRNA cytometry via sequence-specific nanoparticle clustering and trapping,” appeared in the journal Nature Chemistry. "Screening for drug resistance is key to improving treatment approaches for many cancers," Shana Kelley, a University of Toronto professor who was senior author of the study, said in a press release. "It's important for patients not to be on a therapy that won't help them, and it's also important for healthcare systems to avoid, whenever possible, delivering ineffective treatments," she added. The technology focuses on circulating tumor cells, which leave a primary tumor for the blood and can spread the cancer to other pa
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