Tumor-fighting Protein, PTEN, Restored in Mice Prostate Cancer Models Using mRNA and Nanoparticles

Tumor-fighting Protein, PTEN, Restored in Mice Prostate Cancer Models Using mRNA and Nanoparticles
Messenger RNAs encoding for the PTEN protein that were carried in tiny nanoparticles to prostate cancer cells in a proof-of-concept study were able to destroy those cells, preventing tumor growth and progression in several mouse models of prostate cancer, researchers report. PTEN is a potent and well-characterized tumor-suppressor protein, and one encoded by a gene that is lost or mutated in about

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