Phase 1 Trial Enrolling Advanced, Castration-resistent Patients to Test Triple Immunotherapy Combo

Phase 1 Trial Enrolling Advanced, Castration-resistent Patients to Test Triple Immunotherapy Combo
A Phase 1 trial is enrolling people with metastatic castration-resistant prostate cancer (mCRPC) to test Inovio Pharmaceutical's immunotherapy INO-5151 in combination with two other immunotherapies — Celldex’s CDX-301 and Bristol-Myers Squibb’s Opdivo (nivolumab). The PORTER study (NCT03835533) will include 45 patients who were previously treated with second-generation androgen receptor inhibitors (a kind of hormone therapy), such as Zytiga (abiraterone acetate), Xtandi (enzalutamide), or Erleada (apalutamide). The trial, a collaboration between Inovio, the Parker Institute for Cancer Immunotherapy (PICI), and the Cancer Research Institute (CRI), will be conducted at clinical sites in California and New York. For more information, click here. PORTER's main goal is to determine the triple combination's safety
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