PSMA PET-CT Offers Better Detection Rates in Recurrent PC, Study Says

PSMA PET-CT Offers Better Detection Rates in Recurrent PC, Study Says
The imaging agent 68Ga-PSMA-11 has better detection rates than 18F-fluciclovine in men with recurrent prostate cancer who have already had radical surgery to remove the prostate and whose levels of prostate-specific antigen (PSA, a marker of disease) are very low, a study says. The findings of the study, "18F-fluciclovine PET-CT and 68Ga-PSMA-11 PET-CT in patients with early biochemical recurrence after prostatectomy: a prospective, single-centre, single-arm, comparative imaging trial," were published in The Lancet Oncology. Whole-body positron emission tomography-computed tomography (PET-CT) scans are necessary to determine the location and extent of disease in men whose prostate cancer has returned, to select the best course of treatment. However, there is no consensus among different health authorities as to which specific PET-CT imaging agent should be used to identify suspected sites of prostate cancer recurrence in these patients. Guidelines defined by the National Comprehensive Cancer Network (NCNN) have established that 18F-fluciclovine is the most suitable imaging agent
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