New Promising Prostate Cancer Drug Profiled

New Promising Prostate Cancer Drug Profiled
Prostate Cancer DrugA new drug candidate to treat challenging cases of prostate cancer, galeterone (VN/124-1), has provided strong preliminary results in clinical trials, leading the U.S. Food and Drug Administration (FDA) to put it on a fast track for approval. The compound was developed 10 years ago in the laboratories of the University of Maryland School of Medicine and will now enter a Phase III clinical trial in hospitals and clinics across the U.S. and Canada. "I can think of maybe one other drug in the 30 years I've been doing oncology that showed these kind of results. This is an incredibly promising start for this medicine,” Dr. Kevin J. Cullen, director of the University of Maryland's Marlene and Stewart Greenebaum Cancer Center, said in a Baltimore Sun interview. The compound began as collaboration between two Maryland University researchers, Angela M. H. Brodie and Vincent C.O. Njar, as a drug to block production of estrogen in breast cancer. However, Dr. Brodie hypothesized whether the strategy used for estrogen could also be applied towards androgens, testosterone, and dihydrotestosterone, which fuel prostate cancer. One of the most common treatments for severe prostate cancer is drug-induced castration, a procedure that shuts down androgen production from the testicles. However, Dr. Njar and Dr. Brodie were looking for a way to fight prostate cancer that con
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