MD Anderson Researchers Find Gene to Predict Prostate Cancer

MD Anderson Researchers Find Gene to Predict Prostate Cancer
shutterstock_166437050Researchers from The University of Texas MD Anderson Cancer Center have discovered a gene that is able to predict prostate cancer. The biomarker is similar to KLK3, a gene used to predict which severe form of GS7 prostate cancer patients will develop. The findings of the research were published on the official publication of the American Association of Cancer Research, the Clinical Cancer Research journal. The team discovered that the KLK3 gene, a gene present on chromosome 19 that encodes for the prostate-specific antigen (PSA), is related to both prostate cancer aggression and a single nucleotide polymorphism (SNP). Using the Gleason score to predict the effects of prostate cancer associated to the GS7 subtype, the researchers were able to identify the variation. “This is the first report that I am aware of that indicates a genetic variant can stratify GS7 prostate cancer patients,” explained one of the study authors, Jian Gu, Ph.D., associate professor at MD Anderson in the institute's press release. “This is important because this group with heterogeneous prognosis is difficult to predict
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