Sipuleucel-T Found to Have Added Therapeutic Benefit in Prostate Cancer Patients

Sipuleucel-T Found to Have Added Therapeutic Benefit in Prostate Cancer Patients
shutterstock_185401712The German Institute for Quality and Efficiency in Health Care (IQWiG), an independent scientific institute that examines the risks and benefits of medical interventions in patients, recently reported in a press release that sipuleucel-T (trade name Provenge), a cell-based cancer immunotherapy for prostate cancer has added benefit for prostate cancer patients’ clinical outcome. Sipuleucel-T is an autologous cellular immunotherapy where the patient’s own immune system is programmed to recognize metastatic cancer cells and attack them. The patient’s immune cells are extracted from the individual, treated in the laboratory with a specific protein, and injected back into the patient’s bloodstream where they can better identify prostate cancer cells and stimulate the immune system to fight them. Sipuleucel-T was approved by the U.S. Food and Drug Administration (FDA) in September 2014 as a therapy for metastatic prostate cancer in men with few or no symptoms in a phase where they do not require chemotherapy. In January 2015, IQWiG indicated that sipuleucel-T had no added benefit for patients. This conclusion was based on a study conducted by Dendreon Corporation (the sipuleuc
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