MIT Researchers Develop Device That Identifies Which Drugs Can Effectively Treat Cancers Such as Prostate Cancer

MIT Researchers Develop Device That Identifies Which Drugs Can Effectively Treat Cancers Such as Prostate Cancer
Although there are more than 100 approved drugs to treat cancer, predicting which drugs will help a particular patient remains complex. To overcome this issue, MIT researchers developed a small implantable technology that carries up to 30 small doses of different drugs. The study reporting this new device is published in the journal Science Translational Medicine. Following the implantation of this new device in a tumor allowing the drugs to diffuse into the tissue, the investigators can measure the effectiveness of each drug in killing cancer cells. According to Oliver Jonas, paper lead author and postdoc at MIT's Koch Institute for Integrative Cancer Research, this new device can potentially reduce much of the guesswork involved in selecting cancer treatments. "You can use it to test a patient for a range of available drugs, and pick the one that works best," Jonas said in a recent news release. The majority of the drugs targeting cancer damage the DNA and interfere with cell normal function. Currently, researchers have developed targeted compounds that kill tumor cells with particular genetic mutations. Nevertheless, it remains complex to determine the effectiveness of a particular drug in an individual patient. Normally, tumor cells are extracted, grown in lab dishes, and treated with different agents in order to determine which ones are the most efficient. But as Jonas said, this method removes tumor cells from their natural environment, which can play a key role in the tumor response to drug treatment. "The approach that w
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Daniela holds a PhD in Clinical Psychology from The University of Edinburgh, United Kingdom, a MSc in Health Psychology and a BSc in Clinical Psychology. Her work has been focused on vulnerability to psychopathology and early identification and intervention in psychosis.

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