Champions Oncology Says New Xenograft Models Will Aid Prostate Cancer Research

Champions Oncology Says New Xenograft Models Will Aid Prostate Cancer Research
0
(0)

Champions Oncology has added new cohorts of patient-derived xenograft (PDX) models to its TumorBank, expanding the company’s product line in castrate-resistant prostate cancer (CRPC) and other ailments.

The new PDX models will support drug development in oncology programs and in translational industry and academic research.

CRPC is a type of prostate cancer that no longer responds to hormone (ADT) therapy and is continuing to progress. Besides CRPC, the models will be available for hepatocellular cancer, breast cancer, head and neck cancer, acute myeloid leukemia (AML) and non-small cell lung cancer (NSCLC). With this addition, Champions’ TumorBank grows to more than 900 clinically relevant PDX models — 160 of them added in the past six months alone.

“Champions continues to invest in building new models that reflect the evolving standard of care to provide robust model cohorts for pre-clinical research and clinical trial simulation, Angela Davies, Champions’ chief medical officer, said in a press release. She added that the New Jersey-based company’s clinical operations “not only allow for new PDX model-building” but also aim to translate the results of early-phase clinical trials into practical techniques and tools for treating diseases.

Champions bases its technology on the clinical implementation of primary human tumors in immune-deficient mice. It then propagates the resulting engraftments in a way that preserves the original human tumor’s  biological characteristics, allowing physicians to better evaluate specific treatments.

“By making these models commercially available for translational studies at Champions, researchers and pharmaceutical companies will now have access to exclusive animal models integral to drug development research that have been generally inaccessible in the past,” said the company’s CEO, Ronnie Morris, MD.

Inês holds a PhD in Biomedical Sciences from the University of Lisbon, Portugal, where she specialized in blood vessel biology, blood stem cells, and cancer. Before that, she studied Cell and Molecular Biology at Universidade Nova de Lisboa and worked as a research fellow at Faculdade de Ciências e Tecnologias and Instituto Gulbenkian de Ciência. Inês currently works as a Managing Science Editor, striving to deliver the latest scientific advances to patient communities in a clear and accurate manner.
×
Inês holds a PhD in Biomedical Sciences from the University of Lisbon, Portugal, where she specialized in blood vessel biology, blood stem cells, and cancer. Before that, she studied Cell and Molecular Biology at Universidade Nova de Lisboa and worked as a research fellow at Faculdade de Ciências e Tecnologias and Instituto Gulbenkian de Ciência. Inês currently works as a Managing Science Editor, striving to deliver the latest scientific advances to patient communities in a clear and accurate manner.
Latest Posts
  • NCCN and Rubraca
  • Orgovyx and FDA approval
  • Lynparza
  • Erleada results

How useful was this post?

Click on a star to rate it!

Average rating 0 / 5. Vote count: 0

No votes so far! Be the first to rate this post.

As you found this post useful...

Follow us on social media!

We are sorry that this post was not useful for you!

Let us improve this post!

Tell us how we can improve this post?