Mechanism Identified in Cellular Change Driving Castration-Resistant Prostate Cancer

Mechanism Identified in Cellular Change Driving Castration-Resistant Prostate Cancer
Researchers at Moffitt Cancer Center have revealed the mechanism that explains the transformation process of prostate cells into castration-resistant cancer cells. They've also identified a new drug candidate that targets this specific mechanism, preventing the growth and proliferation of these aggressive and deadly cancer cells. The findings were featured in an article titled “ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer,” published in the journal Cancer Cell. Researchers have known for years
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