$26.5M Study to Look at Why Black Men at Higher Risk for Aggressive Prostate Cancer

$26.5M Study to Look at Why Black Men at Higher Risk for Aggressive Prostate Cancer
The National Institutes of Health (NIH) and the Prostate Cancer Foundation launched a $26.5 million large-scale, multi-institutional study to assess how biological and social factors could be associated with aggressive prostate cancer in African-American men. Black men in the U.S. have about a 15 percent chance of developing prostate cancer during their lifetime — 5 percent more than white men — and are also more likely to experience an aggressive form of the disease when compared to men of other racial and ethnic groups. Even more troubling, the risk of dying from prostate cancer in African-American men is double compared to that of Caucasian men. Now, researchers want to understand why these disparities exist and the best way to address them. "No group in the world is hit harder by prostate cancer than men of African descent, and to date, little is known about the biological reasons for these disparities, or the full impact of environmental factors," Jonathan W. Simons, MD, president and CEO of the Prostate Cancer Foundation (PCF), said in a press release. "We celebrate our partnership and applaud NIH for spearheading this study, which we believe will help pave the way for groundbreaking discoveries that will improve health equity for African-American men and their families," he added. The RESPOND study aims to investigate how environmental social stressors and genetic factors could be related to aggressive prostate cancer in Af
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Joana is currently completing her PhD in Biomedicine and Clinical Research at Universidade de Lisboa. She also holds a BSc in Biology and an MSc in Evolutionary and Developmental Biology from Universidade de Lisboa. Her work has been focused on the impact of non-canonical Wnt signaling in the collective behavior of endothelial cells — cells that make up the lining of blood vessels — found in the umbilical cord of newborns.

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