2 Compounds in Coffee Seen to Slow Growth of Prostate Cancer in Early Study

2 Compounds in Coffee Seen to Slow Growth of Prostate Cancer in Early Study
Two compounds found in coffee might be able to slow the growth and migration of prostate cancers, a pilot study conducted in drug-resistant cancer cells and a mouse model report. As such, two possible therapeutic candidates for drug-resistant prostate cancers may have been identified in this work, which also helps in explaining why findings in some studies show regular coffee drinkers with lower prostate cancer risks. The compounds, kahweol acetate and cafestol, were seen, in a dose-dependent manner, to slow the progression of prostate tumors that are resistant to standard therapy in mice. Researchers in Japan plan to continue with this line of study. The study, “Coffee diterpenes kahweol acetate and cafestol synergistically inhibit the proliferation and migration of prostate cancer cells,” was published in The Prostate and presented at the recent 2019 Annual European Association of Urology (EAU) Congress, held in Barcelona. Some evidence suggests a link between drinking certain types of coffee and a lower risk of some cancers, including prostate cancer. A
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Ana is a molecular biologist with a passion for discovery and communication. As a science writer, she looks for connecting the public, in particular patient and healthcare communities, with clear and quality information about the latest medical advances. Ana holds a PhD in Biomedical Sciences from the University of Lisbon, Portugal, where she specialized in genetics, molecular biology, and infectious diseases.

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