Higher Radiation Therapy Doses Over Shorter Time Show No Added Side Effects in Men with Prostate Cancer, Study Says

Higher Radiation Therapy Doses Over Shorter Time Show No Added Side Effects in Men with Prostate Cancer, Study Says
Delivering higher doses of radiation therapy over a shorter time period — an approach called stereotactic body radiation therapy (SBRT) — does not worsen side effects in men with localized prostate cancer, compared to conventional radiation therapy, a Phase 3 trial shows. The study also suggests that SBRT delivered through the CyberKnife System is less toxic for the genitourinary system than conventional linear accelerators used for this kind of radiation therapy. The research was published in an article, “Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): acute toxicity findings from an international, randomised, open-label, phase 3, non-inferiority trial,” in the journal The Lancet Oncology. Accuray’s CyberKnife is a robotic system that delivers SBRT to the prostate and other organs. This approach involves very high doses of radiation over a smaller number of treatment sessions compared to conventional radiation therapy. As the prostate can move unpredictably
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José is a science news writer with a PhD in Neuroscience from Universidade of Porto, in Portugal. He has also studied Biochemistry at Universidade do Porto and was a postdoctoral associate at Weill Cornell Medicine, in New York, and at The University of Western Ontario in London, Ontario, Canada. His work has ranged from the association of central cardiovascular and pain control to the neurobiological basis of hypertension, and the molecular pathways driving Alzheimer’s disease.

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