Higher Radiation Therapy Doses Over Shorter Time Show No Added Side Effects in Men with Prostate Cancer, Study Says

Higher Radiation Therapy Doses Over Shorter Time Show No Added Side Effects in Men with Prostate Cancer, Study Says
Delivering higher doses of radiation therapy over a shorter time period — an approach called stereotactic body radiation therapy (SBRT) — does not worsen side effects in men with localized prostate cancer, compared with conventional radiation therapy, a Phase 3 trial shows. The study also suggests that SBRT delivered through the CyberKnife System is less toxic for the genitourinary system than conventional linear accelerators used for this kind of radiation therapy. The research was published in an article, “Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): acute toxicity findings from an international, randomised, open-label, phase 3, non-inferiority trial,” in the journal The Lancet Oncology. Accuray’s CyberKnife is a robotic system that delivers SBRT to the prostate and other organs. This approach involves very high doses of radiation over a smaller number of treatment sessions compared with conventional radiation therapy. As the prostate can move unpredicta
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