Posts by: Jose Marques Lopes, PhD

Jose Marques Lopes, PhD

November 29, 2018

Finasteride Use Before Prostate Cancer Diagnosis Linked to More Advanced Disease, Lower Survival, Study Finds

News

Patients who take finasteride before being diagnosed with prostate cancer tend to have more advanced and aggressive disease, as well as lower overall survival, according to a large, national study. ... Read more

September 17, 2018

Androgen Deprivation Therapy Can Make Prostate Cancer More Aggressive, Study Finds

News

While androgen deprivation therapy (ADT) is an important treatment for prostate cancer, a new study has found that it sometimes promotes the transformation of prostate cancer cells into a more ... Read more

September 13, 2018

A.I.-guided Chemo Halts Disease Worsening in Patient with mPRPC, Study Reports

News

An artificial intelligence (A.I.) platform called CURATE.AI may be used to determine the optimal doses of investigational therapy ZEN-3694 and Xtandi (enzalutamide) to be given to patients with metastatic castration-resistant ... Read more

August 9, 2018August 9, 2018

First Patient Advanced Prostate Cancer Treated with Harpoon Therapeutics’ HPN424

News

A Phase 1 clinical trial of Harpoon Therapeutics’ immunotherapy candidate, HPN424 for metastatic castration-resistant prostate cancer (mCRPC), has treated the first patient, according to the company. HPN424 uses the Harpoon’s TriTAC (Tri-specific T cell Activating Construct) ... Read more

July 30, 2018July 30, 2018

Eating Dinner Earlier May Help Reduce Prostate, Breast Cancer Risk, Study Suggests

News

Eating dinner earlier and allowing more time between the last meal and sleep may help reduce the risk of prostate and breast cancer, a new study in Spain found. ... Read more

July 23, 2018

Early-onset Prostate Cancer Risk Higher Among Sub-fertile Men Using ICSI Technique, Study Finds

News

Sub-fertile men who require their sperm cells to be injected directly into an egg for conceiving have a much greater risk of developing prostate cancer, particularly its early-onset form, according ... Read more

July 16, 2018July 16, 2018

Phase 2 Trial of Potential Prostate Cancer Vaccine, ProscaVax, Soon to Enroll Early-stage Patients

News

OncBioMune Pharmaceuticals will soon start a Phase 2 clinical trial of its investigational vaccine ProscaVax in people with early-stage prostate cancer. ProscaVax consists of a combination of the PSA protein ... Read more

June 28, 2018

Phase 1/2 Trials Begin for PSMA-R2 Compounds Being Tested for Prostate Cancer Treatment, Diagnostics

News

Two Phase 1/2 clinical trials testing PSMA-R2-based treatment and diagnostic candidates for prostate cancer have begun dosing their first patients, Advanced Accelerator Applications (AAA) announced in a press release. ... Read more

June 18, 2018

Blood Tests May Identify Patients Less Likely to Benefit from Hormone Therapies

News

Two new blood tests that detect a variant of the androgen receptor — a protein that binds male hormones called androgens — may help to predict those advanced prostate cancer patients who would not ... Read more

June 11, 2018

Sotio Starts Phase 1/2 Trial of DCVAC/PCa plus ONCOS-102 in Advanced Prostate Cancer

News

The first patient has enrolled in Sotio‘s Phase 1/2 clinical trial testing the immunotherapy DCVAC/PCa in combination with ONCOS-102 in men with advanced prostate cancer. The patient was enrolled in ... Read more