Combining Two Biopsy Methods Improves PC Diagnosis, Study Shows

Combining Two Biopsy Methods Improves PC Diagnosis, Study Shows
Combining two methods of prostate biopsy — using one guided by magnetic resonance imaging (MRI) along with conventional ultrasound-guided biopsy — results in a more accurate detection of clinically significant prostate cancers than either method alone, a study shows. The researchers hope this combined method will improve clinicians’ current confidence levels in prostate cancer diagnosis and aid in the subsequent selection of appropriate treatment. The study, “MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis,” was published in the New England Journal of Medicine. A prostate cancer diagnosis requires collecting small amounts of prostate tissue for analysis. Transrectal ultrasound-guided (TRUS) 12-core prostate biopsy — which involves the collection of 12 samples of tissue in different sections of the prostate — is the standard method for the initial diagnosis and grading of prostate cancer. However, this method has a low sensitivity, meaning that it results in prostate cancer misclassification. This diagnostic uncertainty has contributed to both undertreatment in men with aggressive disease and overtreatment in men with low-risk disease. Previous studies have shown that MRI-guided biopsy is superior to the standard technique in detecting medium-to-high risk prostate cancer. How
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