testosterone

September 24, 2020September 24, 2020

Phase 1 Trial of Oral Treatment for Metastatic CRPC Doses First Patient

News

A first patient has been dosed in a Phase 1 clinical trial investigating the small molecule inhibitor EPI-7386 as a treatment for metastatic castration-resistant prostate cancer (CRPC), its developer, ESSA Pharma, ... Read more

April 10, 2020April 24, 2020

Gene Variant Seen to Promote Castration-resistant Disease in Whites

News

A variant in a gene that promotes the production of testosterone by prostate cancer cells is linked to poorer survival and the development of castration-resistant disease in Caucasians with metastatic ... Read more

January 20, 2020

Zuclomiphene Safely Eases Hot Flashes Linked to ADT Use, Phase 2 Trial Reports

News

Interim Phase 2 trial results show that Veru‘s experimental treatment zuclomiphene citrate is well-tolerated and significantly reduces hot flashes in advanced prostate cancer patients using androgen deprivation therapy (ADT). These ... Read more

August 16, 2018

Low Protein Intake During Pregnancy Raises Progeny’s Risk of Future Prostate Cancer, Rat Study Finds

News

Consumption of a low-protein diet during pregnancy and breastfeeding may increase the risk of male offspring developing prostate cancer later in life, a rat study suggests. The study, “Maternal Low-Protein Diet Impairs ... Read more

February 12, 2018February 13, 2018

Xtandi Reduces Risk of Metastasis in Castration-resistant Prostate Cancer, Phase 3 Trial Shows

News

Treatment with Xtandi (enzalutamide) reduced the risk of metastasis or death in castration-resistant prostate cancer (CRPC) patients whose cancer has not yet spread beyond the prostate, Pfizer and Japan-based Astellas Pharma recently ... Read more

April 6, 2017

Steroid Estetrol Reduces High Testosterone Levels Associated with Prostate Cancer

News

A steroid called estetrol that is produced only by a fetus’ liver during pregnancy could be used to treat prostate cancer, either by itself or in combination with other hormone ... Read more

January 31, 2017

Treatment Lowers Testosterone Levels in Advanced Prostate Cancer Patients in Phase 3 Trial

News

Foresee Pharmaceuticals has reported positive results from its Phase 3 clinical trial assessing FP-001 LMIS — a ready-to-use, testosterone-lowering treatment — in patients with advanced prostate cancer. Suppressing serum testosterone was the single-arm study’s primary goal. ... Read more

January 31, 2017

Androgen Deprivation Therapy Not Found to Increase Risk of Dementia, Alzheimer’s

News

Prostate cancer patients receiving androgen deprivation therapy (ADT) are not at increased risk of dementia or Alzheimer’s disease, according to a study in the Journal of Clinical Oncology. ADT involves ... Read more

April 1, 2015November 18, 2016

ZYTIGA Receives FDA Approval For Label Update For Prolonged Survival In Metastic Castration-Resistant Prostate Cancer

News

ZYTIGA received approval from the U.S. Food and Drug Administration (FDA) for a label update on March 30, 2015. The approval was based on the results of a Phase 3 clinical study ... Read more

January 14, 2015January 14, 2015

Testosterone Therapy Can Benefit Advanced Prostate Cancer Patients

News

A recent study published in Science Translational Medicine by Johns Hopkins Kimmel Cancer Center researchers has found that testosterone can suppress some types of advanced forms of prostate cancer, while ... Read more