Urine Test Is Unnecessary Before a Man with No Prostate Cancer Symptoms Has Biopsy, Study Suggests

Urine Test Is Unnecessary Before a Man with No Prostate Cancer Symptoms Has Biopsy, Study Suggests
It's unnecessary for a man with no prostate cancer symptoms to have a urine test before a prostate needle biopsy, a Penn State study suggests. The research, “Preoperative urine culture is unnecessary in asymptomatic men prior to prostate needle biopsy,” appeared in the journal International Urology and Nephrology.  Using a needle to obtain a small amount of prostate tissue to examine is the standard procedure for diagnosing prostate cancer. In fact, more than one million prostate biopsies are performed annually. Because a post-biopsy infection can lead to hospitalization and even death, however, researchers have been studying ways to reduce this risk. The American Urological Association recommends that a man take a fluoroquinolone antibiotic before a biopsy to prevent an infection. But its use can lead to bacteria developing resistance to antibiotics. Infections after a needle biopsy may stem from bacteria migrating from the rectum — where the needle is inserted — to the prostate. And bacteria in urine may contribute to an infection. Pennsylvania State University researchers wanted to know if it's worth doing a urine test on men with no prostate cancer symptoms who are scheduled for a needle biopsy. They collected urine from 150 men with no symptoms 14 days before their biopsy. Six had levels of bacteria that could lead to infections. Three had Escherichia coli, one Klebsiella, and two a mixture of bacteria. Only two had levels of bacteria h
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José is a science news writer with a PhD in Neuroscience from Universidade of Porto, in Portugal. He has also studied Biochemistry at Universidade do Porto and was a postdoctoral associate at Weill Cornell Medicine, in New York, and at The University of Western Ontario in London, Ontario, Canada. His work has ranged from the association of central cardiovascular and pain control to the neurobiological basis of hypertension, and the molecular pathways driving Alzheimer’s disease.

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